NCT03532438

WGS of NTM From Sputum of NTM Lung Disease Patients and From Their Environments

Whole Genome Sequencing of Nontuberculous Mycobacterium (NTM) Derived From Sputum Specimen of NTM Lung Disease Patients Living Together and From Their Environmental Samples

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 6 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to identify the genetic closeness of NTM derived from patients living together and from their surrounding environment and to trace the temporal relationship between them.

Detailed description

After NTM isolation is done by using culture, from patients' sputum/bronchoscopic samples and their environmental samples, whole genome sequencing (WGS) will be conducted for all NTM isolates. Phylogenetic analysis will be performed based on single nucleotide polymorphism (SNP) on each NTM.

Conditions

• Nontuberculous Mycobacterium Infection
• Whole Genome Sequencing

Timeline

• Start date: 2018-05-01
• Primary completion: 2019-05-01
• Completion: 2019-05-01
• First posted: 2018-05-22
• Last updated: 2018-05-22

Locations

1 site across 1 country: South Korea