NCT03531385

Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease

Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease and Healthy Controls

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 200 (actual)
• Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital · Other Government
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

There are few studies in the literature regarding increased frequency of neuropathic pain and sleep disturbance and decreased quality of life in Behçet's disease. Frequency of central sensitization was not investigated in patients with Behçet's disease before. In this study, it is aimed to investigate the frequency of central sensitization, neuropathic pain, sleep disorder and quality of life and their relation to each other in Behcet's disease.

Detailed description

Central sensitization reduces the pain threshold in the pain pathways of the nervous system, causing pain sensation to be perceived with lower stimuli and often causing chronic pain. Central sensitization can be seen with many conditions such as neuropathic pain and sleep disorders, as well as with inflammatory diseases such as rheumatoid arthritis. There are few studies in the literature regarding increased frequency of neuropathic pain and sleep disturbance and decreased quality of life in Behçet's disease. Frequency of central sensitization was not investigated in patients with Behçet's disease before. In this study, it is aimed to investigate the frequency of central sensitization, neuropathic pain, sleep disorder and quality of life and their relation to each other in patients with Behcet's disease and healthy controls.

Conditions

• Behcet's Disease
• Central Sensitisation

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Central sensitisation	Central Sensitization Inventory, which is a comprehensive self-report inventory to assess the overlapping symptom dimensions of central sensitisation syndrome will be used to identify participants with central sensitisation.
DIAGNOSTIC_TEST	Neuropathic pain	Frequency of neuropatic pain will be investigated using Pain Detect Questionnaire
OTHER	Sleep disturbance	Assessment of sleep disturbance will be assessed by Pittsburgh Sleep Quality Index
OTHER	Quality of life	Quality of life will be assessed by the Nottingham Health Profile

Timeline

• Start date: 2018-05-22
• Primary completion: 2019-02-01
• Completion: 2019-03-21
• First posted: 2018-05-21
• Last updated: 2019-07-11

Locations

1 site across 1 country: Turkey (Türkiye)