Trials / Withdrawn
WithdrawnNCT03529916
Endothelial Cell Gene Networks of CVD
- Status
- Withdrawn
- Phase
- —
- Study type
- Observational
- Enrollment
- 0 (actual)
- Sponsor
- Tufts University · Academic / Other
- Sex
- All
- Age
- 30 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
The objective of this study is to identify relevant signature gene networks of cardiovascular disease in endothelial cells derived from circulating endothelial progenitor cells of individuals with established cardiovascular disease (CVD).
Detailed description
The investigators propose to enroll CVD and healthy subjects between 30 and 60 years of age, matched for age, gender, body mass index, and medication (statin and anti-hypertensive) use. Circulating endothelial progenitor cells will be isolated from blood and cultured in vitro to differentiate into endothelial cells.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | isolation of endothelial cells precursors in blood | Circulating endothelial precursor cells will be isolated and then cultured in vitro. RNA will be then isolated. |
Timeline
- Start date
- 2018-05-21
- Primary completion
- 2021-09-23
- Completion
- 2021-09-30
- First posted
- 2018-05-18
- Last updated
- 2021-07-28
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03529916. Inclusion in this directory is not an endorsement.