NCT03529201

QLB After Nephrectomy

Effectiveness of Quadratus Lumborum Block After Nephrectomy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 105 (actual)
• Sponsor: Medical University of Lublin · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Oxycodone consumption and postoperative pain intensity in patients undergoing nephrectomy procedures. Of all study participants, 50% will obtain quadratus lumborum block (QLB).

Detailed description

Patients undergoing nephrectomy procedures will be allocated to one of the study arms. At the end of an operation, still under general anesthesia, 50% patients will obtain QLB with ropivacaine. Ultrasound-guided QLB will be performed on the side of surgery with 0.375% ropivacaine solution (0.2 mL per kg). Every patient will get patient-controlled analgesia pump with oxycodone in the postoperative period. Postoperative pain will be measured with VAS (visual-analogue scale) 2, 4, 8, 12 and 24 hours after the end of the operation. 24 -hours period. At the 1, 3, 6 months patients will be interviewed by phone to assess neuropathic pain. Neuropathic Pain Symptom Inventory (NPSI) will be used.

Conditions

• Pain, Postoperative
• Chronic Postoperative Pain

Interventions

Type	Name	Description
PROCEDURE	QLB	On the side of the surgery, QLB with 0.375% ropivacaine (0.2 mL/kg)
DEVICE	PCA	Patient-controlled analgesia
PROCEDURE	GA	General anesthesia
DRUG	Oxycodone	administered by PCA
DRUG	Sevoflurane	Inhalational anesthetic during GA
DRUG	Fentanyl	painkiller during GA
DRUG	Rocuronium	muscle relaxant during GA

Timeline

• Start date: 2018-05-07
• Primary completion: 2019-02-28
• Completion: 2019-08-25
• First posted: 2018-05-18
• Last updated: 2023-11-24

Locations

2 sites across 1 country: Poland