Trials / Completed
CompletedNCT03527680
Effect of Lactobacillus Rhamnosus on Serum Uremic Toxins in Hemodialysis
Effect of Lactobacillus Rhamnosus on Serum Uremic Toxins (Phenol and P-Cresol ) in Hemodialysis Patients: A Double Blind Randomized Clinical Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 42 (actual)
- Sponsor
- nooshin dalili · Academic / Other
- Sex
- All
- Age
- 20 Years
- Healthy volunteers
- Not accepted
Summary
Uremic toxins such as p-cresol and phenol are suggested to be associated with higher mortality in hemodialysis patients. The aim of this study was to investigate the effects of probiotics on serum p-cresol level in hemodialysis patients.
Detailed description
Overall, 42 hemodialysis patients (10 women and 32 men) were divided randomly into the Lactobacillus rhamnosus group (21 patients) and the placebo group (21 patients).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Lactobacillus rhamnosus | daily one capsule containing 1.6\*107 CFU of Lactobacillus Rhamnosus prepared by Tabriz Nutrition Research Center from yogurt and cheese of different farms located in the suburbs Heris, after meal for 28 days |
| DRUG | Placebo - Cap | daily one capsule of placebo |
Timeline
- Start date
- 2016-09-01
- Primary completion
- 2016-11-30
- Completion
- 2016-12-30
- First posted
- 2018-05-17
- Last updated
- 2018-05-17
Source: ClinicalTrials.gov record NCT03527680. Inclusion in this directory is not an endorsement.