NCT03525912

Neuropsychiatric and Cardiovascular Side Effects in Ketamine Analgesic Infusions

Neuropsychiatric and Cardiovascular Side Effects in Ketamine Analgesic Infusions: a Prospective Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 101 (actual)
• Sponsor: Universidad de Antioquia · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Evaluation of neuropsychiatric and cardiovascular side effects of low dose ketamine analgesic infusion for postoperative pain

Detailed description

Postoperative pain is a world wide problem related with surgery. Multimodal analgesia may include ketamine, aimed to decrease opioid adverse effects in postoperative analgesia for major surgery, and risk of chronic postsurgical pain. Ketamine has shown efficacy as adjuvant in multimodal analgesia, however, neuropsychiatric and cardiovascular effects of ketamine at low doses in continue postoperative infusion are less known. This type of adverse effects may compromise appropriated recovery. Objective to determine frequency of delirium, agitation, sedation, hallucinations, bad dreams and cardiovascular changes associated with ketamine analgesic infusion treatment for postoperative pain.

Conditions

• Pain, Postoperative
• Ketamine Adverse Reaction

Interventions

Type	Name	Description
DRUG	Ketamine	continuous infusion of low dose ketamine for postoperative pain

Timeline

• Start date: 2017-07-01
• Primary completion: 2018-03-31
• Completion: 2018-11-14
• First posted: 2018-05-16
• Last updated: 2019-03-28

Locations

1 site across 1 country: Colombia