NCT03525522

Nd:Yttrium Aluminum Garnet Laser Treatment for Lichen Sclerosus

Efficacy of Nd:Yttrium Aluminum Garnet Laser Treatment of Lichen Sclerosus

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Dr Adolf Lukanovič · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study evaluates the efficacy of Nd:Yttrium Aluminum Garnet Laser (Nd:YAG) Treatment of Lichen sclerosus in comparison with topical corticosteroid treatment. Half of participants will receive laser treatment and the other half corticosteroid treatment and the results will be followed for 6 months.

Detailed description

Lichen sclerosus (LS) is a chronic skin disease of unknown cause and very unpleasant symptoms which significantly influences the quality of life of the affected patients. Large majority of LS lesions is located in anogenital region where initial white flat papules usually develop into large, white patches of thin, itchy skin causing fusion of labia minora, narrowing of the introitus and burying of the clitoris. Most common symptoms are itching, pain, soreness, burning, dyspareunia and dysuria all strongly interfering with sexual function and patient's self image. Existing treatment options with systemic and topical medications (oral retinoids, topical steroids) have some drawbacks and recently the use of laser was proposed for treatment of LS. This study evaluates the safety and efficacy of Nd:Yttrium Aluminum Garnet Laser (Nd:YAG) Treatment of Lichen sclerosus in comparison with topical corticosteroid treatment. Half of participants will receive laser treatment and the other half corticosteroid treatment and the results will be followed for 6 months.

Conditions

• Lichen Sclerosus
• Lichen Sclerosus Et Atrophicus

Interventions

Type	Name	Description
DEVICE	Nd:YAG Laser	Three sessions of Nd:YAG treatment every two weeks.
DRUG	Topical corticosteroid Diprosone	3 months of topical corticosteroids Diprosone

Timeline

• Start date: 2016-01-28
• Primary completion: 2018-05-30
• Completion: 2018-05-30
• First posted: 2018-05-15
• Last updated: 2018-05-15