NCT03523936

Gut Microbiota and Antibiotics - Prevention of Side Effects by New Prebiotics

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Turku University Hospital · Other Government
• Sex: All
• Age: 2 Years – 6 Years
• Healthy volunteers: Not accepted

Summary

Antibiotics disturb the balance of gut microbiota causing dysbiosis. The purpose of this double-blind placebo controlled intervention study is to investigate whether a new prebiotic product could prevent the side effects of antibiotics.

Detailed description

Thirty children (2-6 years of age), who require antibiotic treatment assessed by a doctor, will be enrolled in the study. The children will be randomized to receive either the prebiotic product or placebo during the course of antibiotic treatment. The children will give a faecal sample in the beginning and at the end of the study. The samples will be used for the analysis of microbiota and differences in the microbiota between the groups.

Conditions

• Changes in the Gut Microbiota During an Antibiotic Treatment

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Prebiotic product	Prebiotic product used during the course of antibiotic treatment
DIETARY_SUPPLEMENT	Placebo	Placebo

Timeline

• Start date: 2018-06-01
• Primary completion: 2019-12-31
• Completion: 2019-12-31
• First posted: 2018-05-14
• Last updated: 2018-05-14