Clinical Trials Directory

Trials / Completed

CompletedNCT03521882

Timed Interval Measurement of Eotaxin in Stroke Study

Status
Completed
Phase
Study type
Observational
Enrollment
80 (actual)
Sponsor
Royal Devon and Exeter NHS Foundation Trust · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

Stroke is caused by sudden changes in blood flow in the brain. This can be fatal or can result in permanent disability. A fast diagnosis is essential to initiate effective interventions and optimize benefits to patients. There are other diseases that can look like a stroke and these are called "stroke mimics". The quicker that stroke mimics can be ruled out the faster a stroke can be diagnosed and treatment can be given. The investigators may be able to use chemicals in the blood to rapidly confirm that a person has had a stroke. One such chemical is called eotaxin. Eotaxin has been found to be changed in sufferers of a stroke but not in those with stroke mimics. However, more research is needed to confirm the usefulness of eotaxin. This feasibility study aims to provide the foundations to allow a large scale trial of this test. The study aims to recruit participants that have had a stroke or a stroke mimic from the Acute Stroke Unit and Stroke clinic at the Royal Devon and Exeter Hospital. Up to 6 blood samples will be taken from each participant at different times over one week. Eotaxin will be measured in these samples and in participant's leftover samples taken for clinical care. This is needed because the investigators know that the amount of eotaxin changes in the blood after a stroke but we do not know how quickly this change happens and for how long the change occurs. The study will also allow the investigators to understand how many participants will be needed for a large scale trial and the challenges that may be faced in recruiting participants.

Conditions

Timeline

Start date
2017-05-22
Primary completion
2019-05-30
Completion
2019-05-30
First posted
2018-05-11
Last updated
2020-11-06

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT03521882. Inclusion in this directory is not an endorsement.