NCT03519828

Oxidation-reduction Homeostasis in Cognitive Impairment Patients After Stroke

Effects of Oxidation-reduction Homeostasis on Cognitive Impairment in Patients With Ischemic Stroke

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Hui-Sheng Chen · Academic / Other
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Cognitive impairment after ischemic stroke can affect not only the social adaptation ability, but also affect the comprehensive rehabilitation of patients. The damage of cognitive impairment after ischemic stroke is not lower than the body function defect after stroke. Many studies have shown that oxidative stress is one of the pathophysiological mechanisms of ischemic cerebrovascular disease. Many studies have reported that the oxidative-reduction of cells plays an important role in the life activities of organisms, affecting the health, aging and death of the organism. In the recent years, some scholars have suggested that post-stroke cognitive impairment may be related to oxidative-reduction homeostasis of the body, but the relevant evidence is lacking and needs to be further explored. Therefore, the purpose of this study is to explore the effect of oxidation-reduction homeostasis on cognitive impairment in patients with ischemic stroke, and provide a theoretical basis for the prevention and treatment of cognitive impairment after ischemic stroke.

Conditions

• Oxidative-reduction Homeostasis
• Post-stroke Cognitive Impairment

Interventions

Type	Name	Description
OTHER	No intervention has been conducted	It is an observational study, and no intervention has been conducted

Timeline

• Start date: 2018-03-01
• Primary completion: 2018-12-30
• Completion: 2019-01-01
• First posted: 2018-05-09
• Last updated: 2019-07-31

Locations

1 site across 1 country: China