NCT03519776

Variation of Progesterone in IVF Cycles

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (actual)
• Sponsor: ART Fertility Clinics LLC · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

to examine if a natural daytime variation in progesterone levels may explain parts of the inconsistent findings from studies reporting divergent results concerning this matter and will be carried out by several blood samples from the same patient during the day of ovulation triggering.

Detailed description

The impact of the progesterone level at the end of the follicular phase in stimulated IVF/ICSI cycles and its effect on the pregnancy rate and oocyte quality is controversial, which arises from conflicting results in retrospective studies and meta-analyses. This study is assumed to examine if a natural daytime variation in progesterone levels may explain parts of the inconsistent findings from studies reporting divergent results concerning this matter and will be carried out by several blood samples from the same patient during the day of ovulation triggering. If variation is present, the impact of variation on the developing oocyte and embryo quality will be estimated by embryo quality indicators.

Conditions

• Progesterone Resistance

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Progesterone variation	The potential gain for medical caretakers and patients would be a certainty if the progesterone level is affected by variations during daytime

Timeline

• Start date: 2018-05-10
• Primary completion: 2019-02-28
• Completion: 2019-03-31
• First posted: 2018-05-09
• Last updated: 2020-02-26

Locations

1 site across 1 country: United Arab Emirates