Clinical Trials Directory

Trials / Terminated

TerminatedNCT03519256

A Study of Nivolumab or Nivolumab Plus Experimental Medication BMS-986205 With or Without Bacillus Calumette-Guerin (BCG) in BCG Unresponsive Bladder Cancer That Has Not Invaded Into the Muscle Wall of the Bladder

A Phase 2, Randomized, Open-label Study of Nivolumab or Nivolumab/BMS-986205 Alone or Combined With Intravesical BCG in Participants With BCG-Unresponsive, High-Risk, Non-Muscle Invasive Bladder Cancer

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
142 (actual)
Sponsor
Bristol-Myers Squibb · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A study to evaluate the safety and tolerability of nivolumab or nivolumab Plus BMS-986205 with or without BCG in BCG-Unresponsive non-muscle invasive Bladder Cancer.

Conditions

Interventions

TypeNameDescription
BIOLOGICALNivolumabSpecified dose on specified days
BIOLOGICALBCGSpecified dose on specified days
DRUGBMS-986205Specified dose on specified days

Timeline

Start date
2018-08-02
Primary completion
2022-08-22
Completion
2022-08-24
First posted
2018-05-08
Last updated
2023-06-01
Results posted
2023-06-01

Locations

88 sites across 15 countries: United States, Argentina, Australia, Brazil, Canada, Chile, China, France, Hong Kong, Italy, Mexico, Netherlands, Russia, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT03519256. Inclusion in this directory is not an endorsement.