Trials / Completed
CompletedNCT03517059
Study of Dysarthria, and the Appearance of Non-dopaminergic Signs in Idiopathic PARKinson's Disease
Prospective Study of Dysarthria, and the Appearance of Non-dopaminergic Signs in Idiopathic PARKinson's Disease
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 29 (actual)
- Sponsor
- University Hospital, Lille · Academic / Other
- Sex
- All
- Age
- 18 Years – 85 Years
- Healthy volunteers
- Accepted
Summary
Pilot study: * Longitudinal follow up of the PRODY-GI cohort for parkinson's disease (PD) * Observational study of upper and lower axial symptoms' occurence in 30 PD patients in on and off drug conditions, 30 aged matched control subjects and 10 control subjects with supra nuclear palsy * Multi modal approach: functional MRI, clinical , ENT assessment, respiratory assessment, neuropsychological and gait evaluations
Detailed description
Prospective, clinical assessment of : * Cognition and diadochokinetic task during fMRI in 30 PD patients (in off and on condition) * Motor assessment using VICON gait and balance analysis * Pulmonary functional testing in OFF and ON drug condition * Quality of life * Clinical neurological MDS UPDRS , N Fog questionnaire * ENT and speech therapist evaluation in OFF and ON drug condition
Conditions
Timeline
- Start date
- 2017-05-11
- Primary completion
- 2018-11-12
- Completion
- 2018-11-12
- First posted
- 2018-05-07
- Last updated
- 2025-12-23
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03517059. Inclusion in this directory is not an endorsement.