Trials / Completed
CompletedNCT03516565
Matrix Metalloproteinases's in Oral Biofluids During Pregnancy and Postpartum
Modulation of Matrix Metalloproteinases-8, -9 and Endogenous Tissue Inhibitor-1 in Oral Biofluids During Pregnancy and Postpartum
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 114 (actual)
- Sponsor
- Aydin Adnan Menderes University · Academic / Other
- Sex
- Female
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The aim of this study was to investigate salivary and gingival crevicular fluid (GCF) levels of MMP-8, MMP-9 and TIMP-1 during 2/3 trimester of pregnancy and after delivery
Detailed description
MMP-8 and MMP-9 have been reported to reflect the inflammatory status in periodontal tissues and, therefore represent as potential biomarkers of periodontitis. The balance between tissue inhibitors of metalloproteinases (TIMPs) and MMPs play an important role in maintaining the integrity of healthy periodontium.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Saliva collection | |
| OTHER | GCF collection |
Timeline
- Start date
- 2013-04-01
- Primary completion
- 2014-10-15
- Completion
- 2015-09-01
- First posted
- 2018-05-04
- Last updated
- 2018-05-04
Source: ClinicalTrials.gov record NCT03516565. Inclusion in this directory is not an endorsement.