NCT03514030

Clinic Registry Study of Optic Neuromyelitis Spectrum Disease in China

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 400 (estimated)
• Sponsor: Beijing Tongren Hospital · Academic / Other
• Sex: All
• Age: 14 Years
• Healthy volunteers: Accepted

Summary

In 1894, Devic first proposed the concept of neuromyelitis optica(NMO). NMO is an inflammatory demyelinating disease that selectively affects the central nervous system of the optic nerve and spinal cord.In 2004, Lennon and other persons found highly specific AQP4（aquaporin 4）antibodies in NMO patients'sera, and further differentiated between NMO and MS, confirming that NMO is an independent disease.At present, NMO has been widely recognized as an idiopathic and severe demyelinating disease of the central nervous system.In 2015, the international NMO diagnostic team developed the diagnostic criteria based on highly specific AQP4 antibodie.Up to now, in China, there is no data on the number of NMOSD patients, the rate of misdiagnosis, the treatment methods, and the prognosis.This study is committed to build China's NMOSD big data platform to provide the basis for diagnosis, treatment and prognosis of the disease.

Conditions

• NMO Spectrum Disorder;Registry Study

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	serum AQP4-antibody testing method	there are different methods of testing serum AQP4-antibody

Timeline

• Start date: 2018-04-01
• Primary completion: 2020-04-01
• Completion: 2021-04-01
• First posted: 2018-05-02
• Last updated: 2018-05-02

Locations

1 site across 1 country: China