NCT03513406

Comparison of Reversal of Neuromuscular Blockade With Sugammadex Versus Neostigmine Plus Glycopyrolate in Patients Undergoing Burn Surgery

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 7 (actual)
• Sponsor: University of Kansas Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to learn if there is a difference in recovery time when using sugammadex versus neostigmine. The researchers also hope to add further knowledge and data to the safety of using sugammadex in burn patients who are hypermetabolic.

Conditions

• Burns

Interventions

Type	Name	Description
DRUG	Sugammadex	Sugammadex is indicated for the reversal of neuromuscular blockade.
DRUG	Neostigmine	Neostigmine is indicated for the reversal of neuromuscular blockade.
DRUG	Glycopyrrolate	Glycopyrrolate is used in conjunction with neostigmine to prevent neostigmine's muscarinic effects.

Timeline

• Start date: 2018-03-15
• Primary completion: 2023-03-07
• Completion: 2023-03-07
• First posted: 2018-05-01
• Last updated: 2023-09-28

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study