Trials / Unknown
UnknownNCT03508414
Nutritional Approaches in Multiple Sclerosis
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 111 (estimated)
- Sponsor
- Charite University, Berlin, Germany · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this project is to characterize the influence of a ketogenic diet and intermittent therapeutical fasting on the course of the disease, as measured by T2-hyperintense cerebral lesions with magnetic resonance tomography (MRT) in patients with multiple sclerosis (RRMS). The investigators expect in both intervention groups fewer cerebral T2 lesions occurring after 18 months in comparison to the control group and as detectable by MRT. According to current recommendations of the German Society of Nutrition (DGE), the control group receives a vegetarian-focused, anti-inflammatory diet.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | ketogenic diet | Patients receive a ketogenic diet, which is carbohydrate-reduced with a high amount of fat. |
| BEHAVIORAL | Intermittent therapeutical fasting | Patients fast for 1 week every six months. Additionally, the patients do an intermittent fasting, that is to say they do not eat for at least 14 hours a day. |
| BEHAVIORAL | Active comparator | The control group is receiving a vegetarian-focused diet according to the current recommendations of the German Society for Nutrition (DGE) for MS patients. |
Timeline
- Start date
- 2017-04-11
- Primary completion
- 2021-12-01
- Completion
- 2021-12-01
- First posted
- 2018-04-25
- Last updated
- 2021-07-29
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT03508414. Inclusion in this directory is not an endorsement.