Clinical Trials Directory

Trials / Active Not Recruiting

Active Not RecruitingNCT03507010

Ledderhose Disease: Radiotherapy or Not?

Ledderhose Disease: Radiotherapy or Not? A Randomised, Multicentre, Prospective, Double Blind Phase III Trial Investigating the Effect of Radiotherapy on Patients With Ledderhose Disease

Status
Active Not Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
84 (actual)
Sponsor
University Medical Center Groningen · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The aim of the LedRad trial is to determine the efficacy and durability of radiotherapy as treatment for patients with Ledderhose disease and to compare this to the natural course of Ledderhose disease.

Conditions

Interventions

TypeNameDescription
RADIATIONRadiotherapyPatients randomized to the Radiotherapy arm will be treated with electrons and receive a total dose of 30 Gy (two separate courses of five daily fractions of 3.0 Gy each).
OTHERSham RadiotherapyPatients randomized to the sham-radiotherapy will not be treated and the radiotherapy treatment will only be simulated.

Timeline

Start date
2018-01-23
Primary completion
2021-08-15
Completion
2029-03-15
First posted
2018-04-24
Last updated
2024-02-28

Locations

1 site across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT03507010. Inclusion in this directory is not an endorsement.