NCT03504033

Xenon-anesthesia on Patients Undergoing Major Liver-resection

Xenon-anesthesia on Patients Undergoing Major Liver-resection: Randomized Controlled Trial

• Status: Withdrawn
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: RWTH Aachen University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare the postoperative outcome of patients undergoing major liver resection under xenon- compared to desflurane-anesthesia.

Detailed description

The aim of this study is to compare the postoperative liver function and additional outcome parameters of patients undergoing major liver resection under xenon- compared to desflurane-anesthesia. Xenon is known to maintain hemodynamic stability and consecutive tissue perfusion. Together with its potential for ischemic pre-conditioning, we hypothesize a protective effect of xenon on post-operative liver failure and ischemia/reperfusion injury.

Conditions

• Liver Function After Partial Liver Resection

Interventions

Type	Name	Description
DRUG	Xenon	inhalation to maintain anesthesia
DRUG	Desflurane	inhalation to maintain anesthesia

Timeline

• Start date: 2018-04-11
• Primary completion: 2019-09-27
• Completion: 2019-09-27
• First posted: 2018-04-20
• Last updated: 2019-10-29

Locations

1 site across 1 country: Germany