NCT03497598

Preventing Recurrent Urinary Tract Infections With α-D-mannose

Preventing Recurrent Urinary Tract Infections With α-D-mannose: a Prospective, Randomized, Double-blinded Placebo-controlled Trial

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Kantonsspital Aarau · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In this trial, women with history of recurrent urinary tract infections (UTIs) will be followed over the course of 6 months. The women will be randomized either to D- Mannose or Placebo. The primary objective of this study is to investigate if treatment with D-mannose reduces the risk for a UTI recurrence compared to treatment with Placebo. H0: Women with history of recurrent UTIs treated with D-Mannose on average have the same number of recurrent UTIs over the course of 6 months compared to women treated with Placebo. H1: Women with history of recurrent UTIs treated with D-Mannose on average have fewer recurrent UTIs over the course of 6 months compared to women treated with Placebo.

Conditions

• Urinary Tract Infections

Interventions

Type	Name	Description
DRUG	Mannose	The powder is dispensed in 2g neutral sticks and ready to be dissolved in 100ml of water for daily oral ingestion.
DRUG	Lactose	The powder is dispensed in 2g neutral sticks and ready to be dissolved in 100ml of water for daily oral ingestion.

Timeline

• Start date: 2018-05-09
• Primary completion: 2020-05-31
• Completion: 2020-05-31
• First posted: 2018-04-13
• Last updated: 2020-09-02

Locations

1 site across 1 country: Switzerland