NCT03497325

Effect of Autologous Platelet-rich Plasma in Uterine Wound Healing

the Efficacy of Intramuscular Autologous Platelet-rich Plasma Injection on Uterine Wound Healing After Primary Cesarean Section

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 134 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to evaluate the efficacy of intramuscular autologus platelet rich plasma on uterine wound healing after primary cesarean section

Detailed description

110 pregnant female undergoing primary prelabor CS will be randomized to two groups group A)autologus PRP will be prepared from participant venous blood collected from the participants' arm into a syringe primed with ACD-A. then it will be injected into uterus after closing uterine incision . Injection sites will be selected near the incision at evenly 20 different sites group B)normal saline 0.9 will be injected into uterus after closing uterine incision . Injection sites will be selected near the incision at evenly 20 different sites.

Conditions

• Cesarean Section Complications

Interventions

Type	Name	Description
DRUG	autologus platelet rich plasma	55 participant unergoing prelabor primary CS will receive intramyometrial injection of PRP after closure of uterine incision
DRUG	placebo	55 participant unergoing prelabor primary CS will receive intramyometrial injection of normal saline after closure of uterine incision

Timeline

• Start date: 2020-02-01
• Primary completion: 2020-12-15
• Completion: 2020-12-15
• First posted: 2018-04-13
• Last updated: 2021-07-21

Locations

1 site across 1 country: Egypt