NCT03487380

Taxonomic and Functional Composition of the Intestinal Microbiome: a Predictor of Rapid Cognitive Decline in Patients With Alzheimer's Disease

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 86 (actual)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 70 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The objective of the study is to highlight a modification of the composition of the intestinal microbiota associated with the diagnosis of Alzheimer's disease and its most unfavorable form, Rapid Cognitive Decline (DCR). This identification could lead to diagnostic strategies based on the analysis of the intestinal microbiome, and preventive and curative treatments, based on the modulation of intestinal microbiota

Conditions

• Alzheimer Disease
• Intestinal Microbiota

Interventions

Type	Name	Description
PROCEDURE	Fecal sample collection	Fecal sample collection

Timeline

• Start date: 2017-09-04
• Primary completion: 2023-06-12
• Completion: 2023-06-12
• First posted: 2018-04-04
• Last updated: 2024-02-01

Locations

2 sites across 1 country: France