Trials / Completed
CompletedNCT03485248
People Living With HIV/AIDS, Nitrate, Endotelial Function, Arterial Stiffness and Skeletal Muscle Oxygenation
Effect of Ingestion of Beet Juice on Endothelial Function, Arterial Stiffness and Muscle Oxygenation Parameters in People Living With HIV / AIDS Using Antiretroviral Therapy
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- Universidade Federal do Rio de Janeiro · Academic / Other
- Sex
- All
- Age
- 18 Years – 59 Years
- Healthy volunteers
- Accepted
Summary
Administration of antiretroviral therapy has brought benefits for infective human immunodeficiency virus-1 (HIV-1)-patients, reducing the number of AIDS-related morbidity and mortality. However, it is responsible for intensifying complications triggered by the chronic inflammatory state associated with virus infection, such as cardiovascular diseases. The current study evaluated effects of single dose (140mL) of Beetroot Juice (BJ) on macro and microvascular endothelial function in HIV-1-patients undergoing antiretroviral terapy, once BJ was shown to be effective in improving these physiological parameters in uninfected individuals.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Beetroot Juice | 140ml of Beetroot Juice containing on avarege 9 mmol of nitrate |
| DIETARY_SUPPLEMENT | Placebo | 140ml of Beetroot Juice (nitrate free) |
Timeline
- Start date
- 2017-10-18
- Primary completion
- 2018-08-15
- Completion
- 2018-11-28
- First posted
- 2018-04-02
- Last updated
- 2019-04-29
Locations
1 site across 1 country: Brazil
Source: ClinicalTrials.gov record NCT03485248. Inclusion in this directory is not an endorsement.