NCT03484546

Optimum Menstrual Cycle Time for Endometrioma Excision

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Acibadem University · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

This study evaluates the optimum day of menstrual period for the excision of endometriomas to minimize the damage of surgery to normal ovarian tissue. Patients will be grouped as follicular, ovulatory and luteal according to menstrual days. Ovarian damage will be evaluated with both pathologic examination and anti-mullerian hormone levels before and after the surgery.

Detailed description

Endometriosis is a common gynecologic disease seen in about 10% of women in reproductive age. The most common site of endometriosis is overt. Cystic formation of ovarian endometriosis is called endometrioma (chocolate cyst). Definitive treatment of endometriomas is excision by laparoscopy. The disadvantage of this surgery is the removal of some of the normal ovarian follicles within cystectomy material. This procedure can damage the ovarian reserves with the treatment of endometriomas, which are already the cause of infertility, and lead to the conditions such as infertility or early menopause. It has been understood that the ovarian reserves of the patients who underwent endometrioma cystectomy with the decrease of the Anti-Mullerian Hormone values, which is an over reserve parameter.

Conditions

• Endometriosis
• Endometrioma

Interventions

Type	Name	Description
PROCEDURE	laparoscopic endometrioma cyst excision	laparoscopic resection of ovarian endometrioma

Timeline

• Start date: 2018-03-26
• Primary completion: 2021-10-01
• Completion: 2021-10-01
• First posted: 2018-04-02
• Last updated: 2023-10-24

Locations

3 sites across 1 country: Turkey (Türkiye)