NCT03483558

Vegetable Signature From Human Metabolomics Responses

Dietary Intervention Studies on a Variety of Vegetables

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: National Health Research Institutes, Taiwan · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to perform dietary intervention studies on a variety of vegetables.

Detailed description

Plant-based foods have always been an important component of a healthy diet. High intake of plant foods may not only maintain normal bodily functions through the provision of dietary fiber, vitamins, and minerals but also relieve symptoms and prevent diseases. Many studies have pointed out that high intake of plant foods may reduce the incidence of non-communicable disease. Past research investigating the effect of phytochemicals has usually been limited to single substances or single foods. However, a number of researchers have pointed out that phytonutrients and dietary components are likely to act synergistically.Health effects and mechanisms of phytonutrients in combination have not been carefully studied in population settings. The technology of metabolomics has enabled the simultaneous measurement of hundreds of small molecules in biological samples. Exploring the change of metabolites after feeding can not only help us understand the role of plant foods, but may also provide opportunities to assess plant food intake levels.

Conditions

• Vegetable Signature Documentation With Metabolomic Technique

Interventions

Type	Name	Description
OTHER	Control	A standardized diet without any vegetables was provided.
OTHER	Spinach	A standardized diet with 200g spinach was provided.
OTHER	Celery	A standardized diet with 200g celery was provided.
OTHER	Onion	A standardized diet with 200g onion was provided.
OTHER	Mixed Vegetables	A standardized diet with 200g of mixed vegetables (spinach, celery, and onion) was provided.

Timeline

• Start date: 2011-06-11
• Primary completion: 2012-12-31
• Completion: 2015-05-28
• First posted: 2018-03-30
• Last updated: 2018-03-30