NCT03482921

Body Parameters as an Independent Predictor of Acute Pancreatitis

Body Parameters as an Independent Predictor of Acute Pancreatitis: A Propensity Score-matched Case-control Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,662 (actual)
• Sponsor: Ningbo No. 1 Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: —

Summary

This study is to assess the predictive significance of visceral adipose tissue (VAT) and visceral adipose tissue /skeletal muscle tissue ratio (VAT/SMT ratio) for the prognosis in acute pancreatitis (AP) patients.

Detailed description

Acute pancreatitis (AP) is a sudden inflammation of the pancreas. However, one-fifth of patients may develop severe complications with a mortality between 10%-20% It remains a difficulty to find an effective method for prediction of severity of AP at early stage. It is well-established that obesity (defined as body mass index\[BMI\]\>30kg/m2 by the World Health Organization) is a risk factor for AP and increases the incidence of systemic complication, motality. There are a lot of parameters related to saropenic obesity, including areas of visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), skeletal muscle tissue (SMT), and VAT/SMT ratio. it is unclear which parameter is the best predictor of severe AP. Thus, this study is aimed to investigate the association between these parameters and AP severity and find the best predictor of AP.

Conditions

• Acute Pancreatitis

Timeline

• Start date: 2017-12-01
• Primary completion: 2018-02-12
• Completion: 2018-03-22
• First posted: 2018-03-29
• Last updated: 2018-03-29

Locations

1 site across 1 country: China