NCT03480347

The BLF Early COPD Development Partnership Grant

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Imperial College London · Academic / Other
• Sex: All
• Age: 30 Years – 45 Years
• Healthy volunteers: —

Summary

Most existing medical research has focused on patients with well-established COPD and poor lung function. Whilst this is important because such patients have lots of symptoms and problems, in some respects a better way of reducing health problems in the future would be to develop a strategy which focuses on patients with milder disease, and identifies which ones will go on to develop more severe problems and why these problems occur. The research in this application is designed to investigate these issues. The main objective of the Partnership is to study the very early stages of the development of COPD. The investigators will do this by recruiting a novel cohort of smokers (age 30-45), in whom the investigators will follow the trajectories of lung function decline to identify prospectively those at risk of excess decline. This programme forms a unique UK consortium of 8 academic centres with excellent high quality publication records and broad experience in mechanistic, translational, clinical and epidemiological studies in COPD with key capabilities including primary care.

Conditions

• Chronic Obstructive Pulmonary Disease

Timeline

• Start date: 2018-01-17
• Primary completion: 2023-04-30
• Completion: 2023-04-30
• First posted: 2018-03-29
• Last updated: 2021-08-26

Locations

1 site across 1 country: United Kingdom