NCT03479320

Usefulness of Lidocaine in Oral and Maxillofacial Surgeries Under General Anesthesia for Pain Control After Operation

Efficacy of Perioperative Intravenous Lidocaine Infusion on Postoperative Analgesia in Patients Undergoing Oral and Maxillofacial Surgeries Under General Anesthesia

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: B.P. Koirala Institute of Health Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This will be a randomized double blinded clinical study conducted in patients undergoing oral and maxillofacial surgery under general anesthesia. Lidocaine group will receive intravenous bolus 1.5 mg/kg at induction followed by continuous infusion of 2 mg/kg/hr until the completion of surgery.Normal saline group will receive same amount of intravenous normal saline .The primary outcome will be postoperative pain using the NRS scale during first 24 hours and time to first analgesic request

Conditions

• Pain, Postoperative

Interventions

Type	Name	Description
DRUG	Lidocaine	Postoperative analgesic effects will be compared between lidocaine and normal saline group
DRUG	Placebo	Postoperative anlagesic requirements will be calculated and compared with experimental group

Timeline

• Start date: 2018-03-28
• Primary completion: 2018-12-27
• Completion: 2019-03-27
• First posted: 2018-03-27
• Last updated: 2019-04-09

Locations

1 site across 1 country: Nepal