NCT03478553

The Genetics of Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis, a Disease Initiated by Mucociliary Dysfunction

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: University of Colorado, Denver · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study seeks to screen first degree family members of people with Idiopathic Pulmonary Fibrosis (IPF) for the earliest signs of lung fibrosis.

Detailed description

The purpose of this study is to explore genetic factors associated with the development of pulmonary fibrosis. The investigators aim is to identify and explore genetic loci that affect development of pulmonary fibrosis and also explore related environmental exposures. Idiopathic pulmonary fibrosis (IPF) is one of the interstitial lung diseases under the broader umbrella of idiopathic interstitial pneumonias (IIP). The investigators hypothesize that inherited genetic factors are associated with pulmonary fibrosis. To investigate the genetics of pulmonary fibrosis, the investigators plan to enroll individuals with pulmonary fibrosis and their family members.

Conditions

• Idiopathic Pulmonary Fibrosis (IPF)

Interventions

Type	Name	Description
OTHER	Blood draw	Blood draw
OTHER	Questionnaire	Pulmonary Fibrosis Questionnaire

Timeline

• Start date: 2018-01-18
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2018-03-27
• Last updated: 2025-03-25

Locations

1 site across 1 country: United States