Trials / Recruiting
RecruitingNCT03476551
Bariatric Surgery and Pharmacokinetics of Hydrochlorothiazide
Bariatric Surgery and Pharmacokinetics Hydrochlorothiazide: BAR-MEDS Hydrochlorothiazide
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 12 (estimated)
- Sponsor
- Norwegian University of Science and Technology · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on hydrochlorothiazide are investigated.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Hydrochlorothiazide | Patients are tested for their normal prescription hydrochlorothiazide medication |
Timeline
- Start date
- 2016-11-02
- Primary completion
- 2026-10-01
- Completion
- 2026-10-01
- First posted
- 2018-03-26
- Last updated
- 2025-06-06
Locations
1 site across 1 country: Norway
Source: ClinicalTrials.gov record NCT03476551. Inclusion in this directory is not an endorsement.