NCT03475940

Coagulopathy in Cardiac Surgery

Coagulopathy in Cardiac Surgery; a Quaternary-care Academic Center Experience

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 398 (actual)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Coagulopathy in cardiac surgery; a quaternary-care academic center experience Objectives: Primary: To determine incidence of coagulopathy after cardiac surgery in Thai people To determine incidence of resternotomy for stop bleeding, morbidity and mortality Secondary: To identify risk factors which associated with non-red cell transfusion and coagulopathy study decide: Retrospective chart review

Detailed description

Data to be collected: Age\*, gender\* Body weight, height, body mass index\* Underlying disease: DM, renal disease\*, liver disease\* Pre-op. Antiplatelet or anticoagulant\* Pre-op coagulogram and platelet count\* Emergency or elective surgery Resternotomy or not\* Intraoperative blood component Intraoperative factor concentration Dose and timing of antifibrinolytic administration\* CPB time\* Postoperative body temperature\* \*Possible risk factors for non-red cell transfusion statistic: To assess the relationship between risk factors and non-red cell transfusion a univariate analysis was performed using an unpaired t-test and a Chi-square test. For higher accuracy regarding the impact of single risk factors, a multiple logistic regression analysis was also performed.

Conditions

• Coagulopathy, Cardiac Surgery, Cardiopulmonary Bypass

Timeline

• Start date: 2017-12-31
• Primary completion: 2019-06-30
• Completion: 2020-06-30
• First posted: 2018-03-23
• Last updated: 2020-11-17

Locations

2 sites across 1 country: Thailand