NCT03473795

Developing Non-Communicable Disease Registries in Africa : A Step Towards Providing Quality Data for Improving Patient Outcomes

Developing Non-Communicable Disease Registries in Africa: A Step Towards Providing Quality Data for Improving Patient Outcomes

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 6,990 (actual)
• Sponsor: Memorial Sloan Kettering Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This umbrella protocol seeks to develop robust data registries for non-communicable diseases (NCDs) in sub-Saharan Africa (SSA) with the aim of providing accurate and comprehensive data for the evaluation of such diseases in sub-Saharan African countries.Healthy volunteers will be included in the study for comparison. Additionally, the investigators aim to describe the gut microbiome community diversity of a cohort of community dwelling Nigerians and compare with CRC patients in Nigerian and at MSK. We will collect stool for microbiome and metabolomic analysis from community dwelling persons in the catchment area of ARGO facilities in Nigeria while contemporaneously administering an extensive medical and environmental exposure questionnaire.

Conditions

• Non-Communicable Disease

Interventions

Type	Name	Description
BEHAVIORAL	Questionnaire forms	The questionnaires will include information such as socio-demographic data, risk factors, disease specific data, investigation and treatment details as well as findings during followup. Particular reference will be made to outcome measures such as local and distant recurrence, survival and mortality.
OTHER	Bio-specimen samples	Samples can include tissue, blood, urine, saliva, hair and nail clipping.

Timeline

• Start date: 2018-03-16
• Primary completion: 2027-03-01
• Completion: 2027-03-01
• First posted: 2018-03-22
• Last updated: 2026-03-05

Locations

14 sites across 2 countries: United States, Nigeria