NCT03473613

Cabergoline Versus Calcium Infusion in Ovarian Hyperstimulation Syndrome Prevention

Comparison of Cabergoline Versus Calcium Infusion in Ovarian Hyperstimulation Syndrome Prevention:Randomized Controlled Trial

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 230 (actual)
• Sponsor: Benha University · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Giving oral Cabergoline or calcium infusion in women at high risk for developing ovarian hyperstimulation syndrome in context of assisted reproductive technologies aiming in its prevention

Detailed description

Women undergoing in vitro fertilization or intracytoplasmic sperm injection whom were at high risk for developing ovarian hyperstimuation syndrome were received either oral Cabergoline.5mg tablets for 7days starting on ovum pick up day and continued for 7days or received 10ml of 10%calcium gluconate in 200ml normal saline on ovum pick up day and continued for 4days

Conditions

• Ovarian Hyperstimulation

Interventions

Type	Name	Description
DRUG	Oral Cabergoline	Giving oral Cabergoline tablet 0.5 milligram daily starting on ovum pick up day and continued for seven days
DRUG	Calcium Gluconate	Giving 10 ml of 10 % calcium gluconate on 200 ml normal saline solution o.9% intravenously over thirty minutes starting on ovum pick up day and continued for four days

Timeline

• Start date: 2014-10-01
• Primary completion: 2017-04-15
• Completion: 2017-04-15
• First posted: 2018-03-22
• Last updated: 2018-03-29

Locations

1 site across 1 country: Egypt