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Trials / Completed

CompletedNCT03472313

Assessment of the Biodistribution and Safety of [18F]MNI-958 in Healthy Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
2 (actual)
Sponsor
Invicro · Academic / Other
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The overall goal of this protocol is to evaluate the biodistribution of \[18F\]MNI-958 also known as APN-0000455 or PM-PBB3, as a tau targeted radiopharmaceutical.

Detailed description

The overall goal of this protocol is to evaluate the biodistribution of \[18F\]MNI-958 also known as APN-0000455 or PM-PBB3, as a tau targeted radiopharmaceutical. The specific objectives are: * To determine the radiation dosimetry of \[18F\]MNI-958 * To assess the safety and tolerability of a single dose of \[18F\]MNI-958

Conditions

Interventions

TypeNameDescription
DRUG[18F]MNI-958Healthy Volunteers recruited for the study will undergo a single \[18F\]MNI-958 injection and PET scan.

Timeline

Start date
2017-11-14
Primary completion
2018-04-20
Completion
2018-04-20
First posted
2018-03-21
Last updated
2018-10-22

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03472313. Inclusion in this directory is not an endorsement.

Assessment of the Biodistribution and Safety of [18F]MNI-958 in Healthy Subjects (NCT03472313) · Clinical Trials Directory