NCT03472066

Measurement of the Cervix During Pregnancy According to Age of Conization

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 180 (estimated)
• Sponsor: Centre Hospitalier Universitaire, Amiens · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Treatment of precancerous lesions of the cervix by conization has been shown to increase the risk of premature delivery and premature rupture of the membranes. It has now been clearly established that the cervix is a growing organ during adolescence and early adulthood, It has been hypothetized that cervical conization during the growth phase reduced its growth potential, and induced shorter cervix during the upcoming pregnancy. No studies have been conducted investigating the age at which conization no longer had an impact on cervical size during pregnancy. This will help to identify the age at conisation below which patients will be identified as being at risk event, and thus offer increased monitoring and possibly prophylactic management by programmed strapping. We propose to measure the length of the cervix of pregnant patients who have benefited from conization, which is currently recommended by the Collège National des Gynécologues Obstetriciens Français .In addition, the investigators will use a control group consisting of non-con conical, parity-matched pregnant patients in whom a cervical measurement will also be performed.

Conditions

• Cervix; Pregnancy

Interventions

Type	Name	Description
OTHER	Previous conization	a group of women who have been conized,
OTHER	no previous conization	group with asymptomatic patients on routine second trimester echography

Timeline

• Start date: 2018-02-19
• Primary completion: 2019-07-19
• Completion: 2019-08-19
• First posted: 2018-03-21
• Last updated: 2018-03-21

Locations

1 site across 1 country: France