NCT03471689

Multisensory Integration and Pain Perception

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Wake Forest University Health Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 23 Years
• Healthy volunteers: Accepted

Summary

Pain is a predominant disruption of well-being among humans. Feeling pain is a multimodal sensory experience where information is collected and processed from various senses such as sight and touch. Because pain is complex, variable, and experienced differently by each individual, finding more accessible and practical treatments for pain are necessary. Mindfulness meditation (MM) aims to reduce pain by directing focus to perceive thoughts through non-judgmental awareness. Positive reappraisal (PR) is a possible cognitive pain treatment that focuses on changing the meaning of stressful or negative events into positive, benign, valuable, or beneficial. When a stressful event, such as experiencing pain, is positively reappraised, the individual recognizes and engages with the feeling of stress produced by the event and intentionally looks for benefits that change the feeling from negative to positive. The focus of this study is to examine the effect of different cognitive techniques on multimodal innocuous and noxious stimuli. Visual and tactile noxious stimuli will be administered to determine how visual cue integrate to form and modulate the subjective experience of pain. The study team postulates that mindfulness meditation and positive reappraisal will significantly reduce pain in response to multimodal stimulus (visual cue + noxious heat) when compared to a non-manipulation control condition. These findings will be utilized to better understand the multidimensional mechanisms supporting nociception and the cognitive modulation of pain.

Conditions

• Pain
• Regulation, Self

Interventions

Type	Name	Description
BEHAVIORAL	Mindfulness meditation	Participants will be trained to use mindfulness meditation to reduce pain perception.
BEHAVIORAL	Positive reappraisal	Participants will be trained to use positive reappraisal to reduce pain perception.

Timeline

• Start date: 2017-11-08
• Primary completion: 2019-05-01
• Completion: 2019-05-01
• First posted: 2018-03-20
• Last updated: 2019-06-05

Locations

1 site across 1 country: United States