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Trials / Completed

CompletedNCT03463681

A Study of CaBozantinib in Patients With Advanced or Unresectable Renal cEll cArcinoma

A Phase 2 Open Label Study of CaBozantinib in Patients With Advanced or Unresectable Renal cEll cArcinoma Pretreated With One immunochecKPOint INhibiTor (Anti PD1/PDL1): the BREAKPOINT Trial

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
49 (actual)
Sponsor
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · Academic / Other
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Not accepted

Summary

This is an open label single arm, multicenter, phase II study designet To assess the progression free survival (PFS) of cabozantinib in patients pretreated with one immunocheckpoint inhibitor (CPI) in monotherapy or in combination

Conditions

Interventions

TypeNameDescription
DRUGCabometyxcabozantinib 60 mg orally once daily

Timeline

Start date
2018-06-11
Primary completion
2021-04-08
Completion
2021-04-08
First posted
2018-03-13
Last updated
2021-04-26

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT03463681. Inclusion in this directory is not an endorsement.

A Study of CaBozantinib in Patients With Advanced or Unresectable Renal cEll cArcinoma (NCT03463681) · Clinical Trials Directory