NCT03463642

The Efficacy of Different Vitamin D Supplementation Delivery Methods

The Efficacy of Different Vitamin D Supplementation Delivery Methods on Serum 25(OH)D in Humans a Randomised Double-blind Placebo Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 62 (actual)
• Sponsor: University of Wolverhampton · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

To test the efficacy of different vitamin D delivery methods on serum 25(OH)D. Participants randomly assigned to one of seven groups - three placebo groups and 4 active supplement groups receiving 100,000IU vitamin D3

Detailed description

Various delivery methods of vitamin D supplementation are available to consumers but there have been no studies providing evidence of whether one delivery method is superior to others. The researchers wanted to compare the delivery of 100,000IU vitamin D3 by three methods on serum 25(OH)D levels. Two methods of oral supplementation (pill \[prolonged release\] and liquid \[immediate release\]), and delivery through the skin (with and without a penetrator enhancer. Placebo groups were pill, oral liquid and skin applied oil

Conditions

• Vitamin D Deficiency

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	vitamin D3	100,000IU
DIETARY_SUPPLEMENT	Pill	Dicalcium phosphate, microcrystalline cellulose, silicium dioxide, magnesium stearate
DIETARY_SUPPLEMENT	orange syrup	100 drops orange syrup
OTHER	mineral oil	Paraffinum Liquidum,Isopropyl Palmitate,Parfum
DIETARY_SUPPLEMENT	Penetrator	Tangerine essential oil (10ml)

Timeline

• Start date: 2017-02-02
• Primary completion: 2017-04-04
• Completion: 2017-04-04
• First posted: 2018-03-13
• Last updated: 2018-03-14

Locations

1 site across 1 country: United Kingdom