Clinical Trials Directory

Trials / Completed

CompletedNCT03463577

The Safety of Boostrix Following Routine Immunization of Pregnant Women

An Observational, Retrospective Cohort Database Study to Assess the Safety of Boostrix (U.S. Formulation), a Reduced Tetanus, Diphtheria, Acellular Pertussis Vaccine (Tdap), Following Routine Immunization of Pregnant Women in the United States

Status
Completed
Phase
Study type
Observational
Enrollment
65,783 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
Female
Age
Healthy volunteers
Accepted

Summary

The purpose of this study was to assess the safety of Boostrix administered on or after the first day of the 27th week of pregnancy by conducting a post-marketing study that provided safety information to the public and healthcare providers. This was one of the largest cohorts of pregnant women vaccinated with Boostrix in the U.S. Through partnership between Kaiser Permanente Southern California (KPSC) and the sponsor, GlaxoSmithKline (GSK), information about the safety of maternal vaccination with Boostrix and maternal and infant adverse events (AEs) in a community setting was gained.

Conditions

Interventions

TypeNameDescription
OTHERSafety assessment following routine immunization with BoostrixSubject-level data was collected for pregnant women and their infants through the Electronic Health Records.

Timeline

Start date
2018-04-13
Primary completion
2020-08-04
Completion
2020-08-04
First posted
2018-03-13
Last updated
2022-05-18
Results posted
2022-05-18

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT03463577. Inclusion in this directory is not an endorsement.