Clinical Trials Directory

Trials / Completed

CompletedNCT03462706

Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)

A Randomized Trial Comparing the Effectiveness of Polyp Resection Treatments (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
238 (actual)
Sponsor
Indiana University · Academic / Other
Sex
All
Age
40 Years
Healthy volunteers
Accepted

Summary

The study will compare the use of cold snare, hot snare, cold EMR, and hot EMR for polyp resection. Although previous studies have compared two of the potential resection methods, no previous study has evaluated all four of the resection methods.

Detailed description

The optimal method for removal of polyps 6-9 and 10-15 mm in size is not established. In this study, we propose to evaluate four different treatments for polyps (sized 6mm-15mm). The four treatments are cold snaring without injection, hot snaring without injection, cold EMR, and hot EMR. This study aims to help to establish the optimal resection technique for 6-9 and 10-15 mm polyps.

Conditions

Interventions

TypeNameDescription
PROCEDURECold SnareSubjects randomized to Cold Snare Intervention will have any polyps sized 6mm to 15mm removed using cold snare techniques (no electrocautery, no submucosal injection.)
PROCEDUREHot SnareSubjects randomized to Hot Snare Intervention will have any polyps sized 6mm to 15mm removed using hot snare techniques (with electrocautery, no submucosal injection.)
PROCEDURECold EMRSubjects randomized to Cold EMR will have any polyps sized 6mm to 15mm removed using cold EMR techniques (no electrocautery, with submucosal injection.)
PROCEDUREHot EMRSubjects randomized to Hot EMR will have any polyps sized 6mm to 15mm removed using hot EMR techniques (with electrocautery, with submucosal injection.)

Timeline

Start date
2018-02-06
Primary completion
2021-05-14
Completion
2021-05-14
First posted
2018-03-12
Last updated
2023-02-15
Results posted
2023-02-15

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT03462706. Inclusion in this directory is not an endorsement.