Trials / Completed
CompletedNCT03462368
Evaluation of Root Coverage by Connective Graft and Different Root Conditioning Adjunctive Therapies
Effects of Photobiomodulation and Antimicrobial Photodynamic Therapy Associated With Subepithelial Connective Tissue Graft on the Root Coverage of Multiple Gingival Recessions: A Randomized Controlled Clinical Trial.
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- University of Sao Paulo · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study was to evaluate the effect of two different treatment agents used in conjunction with subepithelial connective graft technique on root coverage outcomes in multiple recession defects. Half of patients will receive root treatment with antimicrobial photodynamic therapy and the other half will receive photobiomodulation therapy by laser on surgery site.
Detailed description
Antimicrobial photodynamic therapy has been widely used in Periodontics to obtain reduction of periodontopathogenic bacteria with absence of systemic side effects and minimal bacterial resistance. Also, it has properties of root demineralization and exposure of collagen fibers. These properties may enhance root coverage in procedures of subepithelial connective graft. Laser photobiomodulation has the potential to increase healing and repair, this can generate gains in the root coverage and dental hypersensitivity.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Control | In the procedure of subepithelial connective tissue graft, exposed dental roots will be treated by scaling and root planing only. |
| PROCEDURE | antimicrobial photodynamic therapy | In the procedure of subepithelial connective tissue graft, exposed dental roots will be treated by antimicrobial photodynamic therapy with toluidine blue O (10mg/ml) |
| PROCEDURE | Photobiomodulation | After the procedure of subepithelial connective tissue graft the whole surgical site will receive red laser application. |
Timeline
- Start date
- 2018-04-01
- Primary completion
- 2019-11-28
- Completion
- 2019-11-28
- First posted
- 2018-03-12
- Last updated
- 2023-02-27
Locations
1 site across 1 country: Brazil
Source: ClinicalTrials.gov record NCT03462368. Inclusion in this directory is not an endorsement.