NCT03454802

Passive Leg Raising - an Important Diagnostic Manoeuvre

Passive Leg Raising - an Important Diagnostic Manoeuvre and Its Dependency on the Activity of the Autonomous Nervous System in Critically Ill Patients and Healthy Subjects

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: Region MidtJylland Denmark · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The aim is to describe the physiological background for PLR and the interpretation of a PLR manoeuvre. The protocol entails the measurement of stroke volume (SV) at baseline (semirecumbent patient position), during PLR and after returning to semirecumbent position. Simultaneously blood pressure (BP), pulse rate (PR), pulse oximetric saturation (SpO2) and ECG are recorded. The procedure is performed in ten normal subjects, ten patients recruited in the cardiology outpatient department and ten critically ill patients under analgosedation in the ICU. Analysis includes changes in measured variables and heart rate variability in the frequency domain during the three phases of the experiment.

Detailed description

See above

Conditions

• Cardiovascular Insufficiency

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Passive Leg Raising	See above

Timeline

• Start date: 2018-09-01
• Primary completion: 2020-10-01
• Completion: 2020-10-01
• First posted: 2018-03-06
• Last updated: 2021-09-24

Locations

1 site across 1 country: Denmark

Regulatory

• FDA-regulated device study