Trials / Completed
CompletedNCT03454711
Functional Magnetic Resonance Imaging (fMRI) Exploration of Neurocognitive Processes Involved in Food Addiction (FA) in Obese Patients: Towards New Phenotypic Markers for an Optimized Care Pathway
- Status
- Completed
- Phase
- Phase 2 / Phase 3
- Study type
- Interventional
- Enrollment
- 47 (actual)
- Sponsor
- Rennes University Hospital · Academic / Other
- Sex
- Female
- Age
- 30 Years – 50 Years
- Healthy volunteers
- Not accepted
Summary
Identification of the cerebral fMRI phenotype of obese patients with FA in cognitive task context based on food choice making
Detailed description
Obesity is a worldwide epidemic associated with many complications. The treatment of obesity is a failure if it does not take into account eating disorders. Among them, food addictions seem to be frequent among obese patients. Clinical diagnosis and therapeutic approaches depend on presence of these FA. Moreover, eating disorders are associated with visible brain abnormalities in fMRI but the cerebral fMRI phenotype of FA is not known.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | fMRI | Brain MRI |
| DEVICE | Indirect calorimetry | Resting energy expenditure |
| DEVICE | Bioimpedance | Measurement of body composition |
| BIOLOGICAL | Lipid profile, glucose, HBA1c, metabolomic analysis | Blood sample |
| BEHAVIORAL | YFAS questionnaire, Binge Eating Scale, Hospital Anxiety and Depression (HAD) scale, hedonic evaluation test (liking) | Questionnaires to characterize eating habits and depression |
Timeline
- Start date
- 2018-04-26
- Primary completion
- 2021-09-08
- Completion
- 2021-09-08
- First posted
- 2018-03-06
- Last updated
- 2023-08-01
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03454711. Inclusion in this directory is not an endorsement.