Trials / Completed
CompletedNCT03454217
Impact of Tramadol and Oxycodone on Sleep Apnea
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- Centre Hospitalier Universitaire Vaudois · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Postoperative pain is usually treated with opioids. Among them, oxycodone is popular in the daily practice as it is administered orally and is easily titrated. However, side-effects include increase duration and frequency of apneic episodes. Some authors believe that tramadol has less impact on these apneic episodes during the first postoperative night, based on a trial that reported conclusive results only during the first 2 postoperative hours. The objective of this randomized controlled trial is to compare the effect of postoperative pain treatment of oxycodone with tramadol on apneic episodes during the first and third postoperative nights.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Oxycodone | Postoperative pain treatment with oxycodone |
| DRUG | Tramadol | Postoperative pain treatment with tramadol |
Timeline
- Start date
- 2018-03-01
- Primary completion
- 2020-09-30
- Completion
- 2020-09-30
- First posted
- 2018-03-05
- Last updated
- 2021-01-27
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT03454217. Inclusion in this directory is not an endorsement.