NCT03452735

Fertility Study of Women With Chronic Inflammatory Rheumatism

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 2,900 (estimated)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Etiopathogenesis of Chronic inflammatory rheumatisms (CIR) includes genetic, autoimmune and environmental factors. Their impact on the quality of life is important, leading to a sometimes severe disability. Thus they are likely to affect female fertility through several mechanisms, including autoimmune since the association between immunity and fertility has already been demonstrated in other autoimmune diseases. This study wants to evaluate and compare the birth rate between CIR and control group.

Detailed description

Data collection will be carried out using a questionnaire submitted to women in charge of the rheumatology department of the University Hospital of Toulouse and having agreed to participate: * women with Rheumatoid arthritis, Psoriatic arthritis, Ankylosing spondylitis or Chronic juvenile arthritis for the chronic inflammatory rheumatism group * women with a mechanical rheumatic pathology for the control group The primary endpoint was birth rate after spontaneous or induced pregnancy in patients who attempted to procreate, in the CIR group and in the control group.

Conditions

• Arthritis, Psoriatic
• Arthritis, Rheumatoid
• Ankylosing Spondylitis
• Chronic Juvenile Arthritis

Interventions

Type	Name	Description
OTHER	Questionnaire about fertility	Sending a questionnaire about fertility that will have to be returned to us in order to be included in the study. The questionnaires, anonymous, will be numbered according to their order of return.

Timeline

• Start date: 2018-07-16
• Primary completion: 2019-07-01
• Completion: 2019-07-01
• First posted: 2018-03-02
• Last updated: 2018-07-23

Locations

1 site across 1 country: France