Clinical Trials Directory

Trials / Unknown

UnknownNCT03451942

The FLOT Regimen Conversion Therapy of Adenocarcinoma of the Stomach / Gastroesophageal

The Clinical Study of FLOT Regimen Conversion Therapy of Her-2 Negative and Single Site Metastasis Adenocarcinoma of the Stomach / Gastroesophageal

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
112 (estimated)
Sponsor
Henan Cancer Hospital · Other Government
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Evaluate survival benefit of surgical treatment after FLOT regimen conversion therapy of Her-2 Negative and single site metastasis adenocarcinoma of the stomach / gastroesophageal compared with chemotherapy, use relevant biomarkers to evaluate the efficacy of chemotherapy and seek for patients with Her-2 negative and metastatic adenocarcinoma of the stomach / gastroesophageal surviving benefit from surgical treatment after the FLOT regimen conversion therapy.

Conditions

Interventions

TypeNameDescription
DRUGFLOT regimen chemotherapyFLOT regimen chemotherapy
PROCEDURED2 gastric and imaging metastases resectionAfter received 4 cycles FLOT regimen chemotherapy , D2 gastric resection and imaging metastases resection was performed. Then continue 4 cycles of FLOT regimen chemotherapy (Chemotherapy begins within 4-6 weeks after surgery)

Timeline

Start date
2018-02-05
Primary completion
2019-09-01
Completion
2021-03-01
First posted
2018-03-02
Last updated
2018-03-02

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT03451942. Inclusion in this directory is not an endorsement.