Trials / Completed
CompletedNCT03449186
Th17 Inducing Cytokines Pregnancy and After Postpartum
Interleukin-17 and Th17 Inducing Cytokines Exacerbate Periodontal Disease During Pregnancy and Postpartum
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 114 (actual)
- Sponsor
- Aydin Adnan Menderes University · Academic / Other
- Sex
- Female
- Age
- 19 Years – 40 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study was to investigate salivary and gingival crevicular fluid (GCF) levels of IL-17A, IL-17E, IL-6 AND IL-23 during 2/3 trimester of pregnancy and after delivery.
Detailed description
IL-17 have a synergytic effect with IL-6 and IL-23. IL-17A levels elevated with periodontal diseases. Many systemical chronic conditions such as atherosclerosis and cardiovascular disease, pregnancy may contribute increasing of IL-17 family cytokine.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Saliva collection | |
| OTHER | GCF collection |
Timeline
- Start date
- 2013-04-01
- Primary completion
- 2014-04-01
- Completion
- 2018-01-01
- First posted
- 2018-02-28
- Last updated
- 2018-02-28
Source: ClinicalTrials.gov record NCT03449186. Inclusion in this directory is not an endorsement.