NCT03448588

Research on Association Between Selenium Deficiencies and Change of Thyroid Function

Effect of Selenium Deficiency on Thyroid Function

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Peking Union Medical College Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

As one of the essential micronutrients, selenium has important biological functions. However, an effective and convenient method for evaluation of selenium nutritional status has not yet been established. Previous literature has disclosed effect of selenium deficiency on inactivating glutathion peroxidase and deiodinase, which may cause decreased conversion from thyroxine ( T4) to triiodothyronine (T3). A case-control study is designed to demonstrate the association between selenium deficiency and abnormally elevated T4 or T4/T3, which may provide more clues for establishing effective selenium assesment methods.

Conditions

• Selenium Deficiency

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	detection of serum selenium	For this case-control study, no intervention will be administered to participants, only serum sample will be collected for selenium assessment

Timeline

• Start date: 2018-04-01
• Primary completion: 2018-12-31
• Completion: 2019-04-01
• First posted: 2018-02-28
• Last updated: 2018-05-23

Locations

1 site across 1 country: China