NCT03448133

rTMS for the Treatment of Primary Progressive Aphasia: A Randomized Controlled Trial

Repetitive Transcranial Magnetic Stimulation for the Treatment of Primary Progressive Aphasia: A Randomized Controlled Tria

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Peking Union Medical College Hospital · Academic / Other
• Sex: All
• Age: 35 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The primary progressive aphasia (PPA) is a neurodegenerative condition characterized by a gradual, irreversible decline of language function (Mesulam, 2001). There are no known treatments for PPA so far. The relentless progression of PPA symptoms eventually leads to a profound impairment in communication ability and, ultimately, to more generalized deficits of cognition. Some cases and small studies reported that Transcranial Magnetic Stimulation (TMS), one of the non-invasive neuromodulation tech, can be employed to facilitate language production and improve the language ability in patients with PPA. Herein we will explore the tolerance and efficacy of TMS for the treatment of PPA by the randomized controlled trial .Meanwhile the functional MRI tech will be used to investigate the neural network changing in the procedure

Conditions

• Aphasia, Primary Progressive
• Repetitive Transcranical Magnetic Stimulation

Interventions

Type	Name	Description
DEVICE	Magstim rTMS	The device is made in London,UK

Timeline

• Start date: 2018-03-01
• Primary completion: 2021-10-31
• Completion: 2021-12-31
• First posted: 2018-02-27
• Last updated: 2020-06-05