NCT03446937

Effect of Antenatal Corticosteroids on Neonatal Morbidity.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: Ahmadu Bello University Teaching Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 49 Years
• Healthy volunteers: Accepted

Summary

It will be a randomized controlled trial. There will be two study groups. Study group 1 will be given dexamethasone while study group 2 will be given betamethasone. The control group will be given placebo.

Detailed description

The study will be a double blind randomised controlled trial. There will be two study groups and one control group. The first study group will be the pregnant women at risk of late preterm birth that will receive antenatal corticosteroids in the form of intramuscular dexamethasone sodium phosphate. The second study group will be the pregnant women at risk of late preterm birth that will receive antenatal corticosteroids in the form of intramuscular betamethasone sodium phosphate. The control group will be pregnant women at risk of late preterm birth that will be given intramuscular water for injection.

Conditions

• Neonatal Respiratory Distress Syndrome

Interventions

Type	Name	Description
DRUG	Dexamethasone Sodium Phosphate Injection	Dexamethasone sodium phosphate injection 12 mg X doses to be given 12 hours apart
DRUG	Betamethasone Sodium Phosphate Injection (Medication)	betamethasone sodium phosphate injection12mg X 2 doses given 12 hours apart
DRUG	Water for injection	Two doses of intramuscular injection of water for injection given 12 hours apart

Timeline

• Start date: 2017-12-01
• Primary completion: 2019-05-31
• Completion: 2019-05-31
• First posted: 2018-02-27
• Last updated: 2019-12-27

Locations

1 site across 1 country: Nigeria